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CBD

What It Is, Types, How It Works

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Full-spectrum CBD is a substance that contains all of the naturally occurring extracts found in the cannabis plant, including very low levels of THC, the psychoactive ingredient associated with the high in marijuana.

It recently became known for its potential to relieve a wide variety of health conditions including pain, anxiety, inflammation, and epilepsy, but more research is needed to fully substantiate any claims about its benefits.

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What is it

Before diving into full-spectrum CBD, it is helpful to understand what CBD to begin with. CBD – short for cannabidiol – is a so-called cannabinoid, one of more than 100 chemical compounds found in the cannabis sativa plant. Most CBD products are made from the hemp varieties of this plant.

The two most famous cannabinoids are CBD and THC:

  • Cannabidiol (CBD) is is often derived from hemp and does not usually cause a “high” on its own.
  • Tetrahydrocannabinol (THC) is the psychoactive compound that causes the euphoric “high” feeling associated with marijuana.

The cannabis plant

Both hemp and marijuana are types of the cannabis plant, and both contain CBD – but hemp plants have 0.3% THC or less, while marijuana plants have higher levels of THC.

Types

Since federal law in 2018 legalized the cultivation and sale of hemp in the United States, CBD has appeared everywhere in a variety of forms – from tablets to oils to creams and gums.

Full-spectrum CBD is one of three main types of CBD that are available. It’s important to understand the differences between the most common types as the ingredients vary.

  • Full spectrum CBD contains CBD and all other cannabinoids, including traces of THC (0.3% or less).
  • Isolate CBD contains only CBD.
  • Broad spectrum CBD contains CBD and several other cannabinoids, but no THC.

Some CBD connoisseurs consider full-spectrum CBD products to be more effective than the other forms because they contain all of the compounds from the cannabis plant plus up to 0.3% THC. This combination creates what researchers have called the “entourage effect,” which means that all of the elements in full-spectrum CBD can work together better than a single cannabinoid used on its own.

How it works

The main cannabinoids in full-spectrum CBD – CBD and THC – act on different areas of the brain. Researchers are still studying their full effects on the body, but they have found that cannabinoids generally help regulate the body’s endocannabinoid system.

This system is responsible for the functioning of the nervous and immune systems, along with mood, the sleep cycle, regulating the inflammatory response and more. Basically, the endocannabinoid system helps correct many different imbalances in the body through activated receptors found in our central and peripheral nervous systems.

It’s also related to the way we experience pain, leading researchers to believe that CBD helps the body’s systems achieve better balance.

Services

So far, the U.S. Food and Drug Administration (FDA) has approved a cannabis-derived drug, a prescription drug used to treat certain severe forms of epilepsy, a condition that causes seizures.

While there is currently no solid scientific evidence of other specific health conditions that may help treat full-spectrum CBD, research suggests that it is not only anti-inflammatory, but also shows promise in treating anxiety, panic, obsessive-compulsive disorder, and post-traumatic disorders Stress disorder in some people.

Risks

Here’s the million dollar question: Does full-spectrum CBD get you “high” because it technically contains traces of THC? In general, experts say no, it shouldn’t produce a “high”. However, the answer is not crystal clear and can vary depending on the product and person.

The levels of THC in full-spectrum CBD are as low as less than 0.3%, which is considered fairly insignificant. Many experts agree that such a small amount is unlikely to be strong enough to have significant psychoactive effects and would likely not register on a drug test, but you shouldn’t rule out these possibilities.

Some people may experience some of the milder psychoactive or sedative effects associated with THC, and the chances are that this could show up on a drug test.

Side effects

Because the research on full-spectrum CBD is still pretty preliminary, experts don’t have all the answers to many consumer questions about the pros and cons of using it for various health problems. However, a 2018 report by the World Health Organization (WHO) shows that CBD is generally generally well tolerated, with reported side effects usually occurring as a result of drug interactions.

However, there is still a chance that you will experience the following side effects:

  • Mood swings
  • Appetite changes
  • diarrhea
  • dizziness
  • sleepiness
  • Dry mouth
  • nausea
  • Vomit

Keep in mind that full-spectrum CBD is not regulated by the FDA, although the agency is currently working on how it might regulate the CBD industry in the future. There is currently no guarantee that a full-spectrum CBD product will be safe or effective for you.

There are no standard and guidelines for daily use, and ingredients and dosages can vary widely. It’s also worth noting that, according to some studies, mislabeling appears to be a fairly common problem with CBD products.

It is a good idea to carefully read the label and ingredients list. You should look for any additional preservatives, flavors, or other ingredients that you are not familiar with and check them online or have them verified by a trusted medical source.

While you don’t need a prescription for full-spectrum CBD, you should speak to your doctor or health care professional to make sure it doesn’t interfere with other medications you are taking and to make sure you are using it for the disease, for the one Using it makes sense based on what we know about the substance.

legality

You may be confused about the legality of full-spectrum CBD. As mentioned, hemp-derived CBD products containing less than 0.3% THC are federally legal, but may not be legal under the laws of some states. You should check local laws before purchasing any CBD products (full-spectrum or not) and before traveling to other states with CBD products.

The decision to try full-spectrum CBD may depend on whether you are okay with consuming THC in any amount, especially if marijuana or CBD are not legal in your state or you expect to be tested for drugs.

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CBD

Pressure BioSciences Nanoemulsion Platform Will Bring More Effective, More Shelf-Stable CBD-Infused Beverages to the Market by End of 2021

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Image provided by Pixabay

CBD-infused beverages will soon be available to consumers worldwide thanks to the nanoemulsion-producing Ultra Shear Technology ™ (UST ™) platform developed by Print BioSciences, Inc (OTCQB: PBIO). With a projected average annual growth rate (CAGR) of 21.2% over the next 7 years, the CBD market is projected to become 13 billion stable, water-soluble versions of the CBD oil by 2028 to allow for more predictable dosing and degradation during the Reduce distribution and storage. That is exactly what the new UST platform from Pressure BioSciences (PBI) did. How it works and what it means for consumers.

Why consumers need a water-soluble version of CBD

CBD is an oil-soluble compound found in cannabis plants. When extracted from the plant, it has no psychoactive side effects, but still offers many of the mental and physical health benefits that cannabis is known for.

Researchers have found that CBD has the potential to manage anxiety, reduce stress, and even reduce the severity of psychotic symptoms in schizophrenic patients. It also shows potential as a powerful anti-inflammatory agent, making it possible to relieve muscle and joint pain, treat symptoms of rheumatoid arthritis, and prevent or slow the growth of cancer cells.

Most importantly, all of these potential benefits come with few or no adverse side effects, which sets CBD-based treatments apart from many of the existing standards of care for these conditions, which are often associated with unpleasant or even harmful side effects.

However, the incredible potential of CBD-based treatments and wellness products has yet to be fully realized. While vegetable oil versions of CBD are already on the market, these oil-based products are not well absorbed by the human body, making it difficult for consumers to take full advantage of the compound.

The World Health Organization estimates that only 6% of CBD oil is actually absorbed when ingested or applied topically. The rest goes through the body, unused and wasted. As a result, the dosage is difficult to predict and the potential health benefits of the cannabis derivative are reduced by the inability of the body to fully absorb the oil.

The story goes on

PBI’s UST platform is helping CBD oil reach its potential

While the search for a method to reliably and consistently convert CBD oil into a water-soluble product that is more easily absorbed has continued, researchers have had little luck so far. Dr. Christopher Hudalla, President and Chief Scientific Officer (CSO) at ProVerde Labs, which tests cannabis-derived materials, commented on the lack of availability of cannabis-based products that are both truly water-soluble and shelf-stable for long enough to be marketable.

ProVerde’s CSO stated, “The introduction of a new technology platform that can consistently produce the ultra-small droplet size nanoemulsions necessary for reliable shelf life of over 1 year, including resistance to freeze-thaw challenges, will be a be a critical turning point and an explosive growth opportunity in the CBD and cannabis product industries. “

This new technology is PBI’s UST platform, which uniquely combines extremely high pressures with intense shear forces to break down CBD oil into droplets so small that the human body can effectively absorb the medicinal compound contained in the oil at significantly higher rates .

In addition, the nano-sized droplets are small enough to withstand regrowth into larger droplets – a problem that leads to this separation and deposition that you see in other emulsions like salad dressings or nut butters. Even with repeated freezing and thawing, a tried and tested test to determine long-term stability, the nanoemulsions made with UST do not separate from PBI or do not decompose.

PBI’s innovative technology makes it possible to ship CBD-enriched beverages worldwide and store them for longer periods of time without fear of the product losing its potency and effectiveness. As a result, consumers will have access to more effective and precisely dosed CBD beverages than ever before. PBI is partnering with industry leaders in the food and beverage space to bring the groundbreaking new CBD infusions to market before the end of 2021.

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© 2021 Benzinga.com. Benzinga does not offer investment advice. All rights reserved.

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CBD

Study Suggests Hemp Extract Is An Effective Weight-Loss Aid

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A proprietary hemp extract shows promise as a supplement for promoting weight loss, according to a study funded by a grant from the National Institutes of Health. Data from the double-blind, placebo-controlled study showed that all 100 participants who took Nitro-V hemp extract daily lost weight and lost up to 22 pounds over 90 days. The minimum weight loss for those taking the supplement was 5 pounds, while 64% of participants in the placebo group either gained weight or saw no change.

The study participants who took the hemp extract, which is high in cannabidiol (CBD), tetrahydrocannabivarin (THCV), cannabidivarin (CBDV), and other cannabinoids, also showed improvements in other metabolic health metrics and important wellness indicators without changing their diet and exercise habits to change. Participants who took Nitro-V saw their body mass index (BMI) decrease an average of three points and lost an average of 2.4 inches from their waist measurements. On average, the study participants in the placebo group gained weight and saw that their BMI remained the same.

Cannabis (hemp) extract.

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Almost 75% of Americans are overweight

According to data from the CDC, more than 73% of adults 20 years or older in the United States are overweight or obese. The health risks associated with obesity can be serious and include heart disease, diabetes, and high blood pressure. Additional CDC data shows that between 2013 and 2016, more than 49% of American adults reported trying to lose weight in the past 12 months.

“Those working to lose weight and improve their overall health are looking for every benefit they can find to help them stick to their exercise and nutrition plans,” said Arthur Jaffee, CEO of Nitro-V manufacturer ECS Brands , in a press release. “Given the results of these studies, we believe that Nitro-V could be the tool to help many achieve their weight loss potential and feel better.”

To conduct the clinical study, which had not yet been published in a peer-reviewed journal, the researchers assembled a group of 125 subjects to participate in the research. A total of 100 participants received either one or two 50 mg servings of Nitro-V daily, the remaining 25 participants received a placebo. Study participants were not told that they were participating in a weight loss study and that they had not changed their diet or exercise habits.

At the beginning and end of the 90-day study period, participants visited the Mayo Clinic campus in Scottsdale, Arizona and completed standardized surveys on health determinants such as diet, appetite, anxiety, and pain. The researchers also monitored the subjects’ weight, BMI, waist circumference, and vital signs, and performed full blood tests to measure blood sugar, cholesterol, and organ health, as well as other diagnostic tests. A statistician analyzed the data collected during the study to identify trends and evaluate the importance of the results. The research was funded by a small business owned by the National Institutes of Health and conducted by a contract researcher with 20 years of experience in product safety studies.

Each softgel microcapsule serving of Nitro-V contains 50 mg of hemp extract with a combination of cannabinoids such as CBD, THCV and CBDV in an organic hemp seed oil base. The solvent-free hemp extract contains the full cannabinoid profile of the source plant, including less than 0.1% THC. Further processing increases the THCV and CBDV levels in the supplement.

The “thin cannabinoid”

Cannabinoids from cannabis, including hemp, act on the body’s endocannabinoid system, which helps maintain physiological, cognitive, and emotional stability. Research has shown that THCV can act as an effective appetite suppressant, which has earned it the nickname “thin cannabinoid”. Other studies have shown that THCV can also help regulate blood sugar levels. THCV also has anti-inflammatory and antispasmodic properties.

Nitro-V hemp extract softgels from ECS Brands.

Photo courtesy of ECS Brands

Jaffee notes that recent research has shown that CBD and THCV can affect lipid and glucose metabolism in animals, both important factors in maintaining a healthy weight. The study also found that CBD had several positive effects on hyperglycemia, largely due to its anti-inflammatory and antioxidant properties. Further evidence from animal studies shows that CBD modulates the cardiovascular response to stress, which plays a role in weight gain and loss. However, the link between CBDV and weight loss is “less direct,” he says.

“Research shows that CBDV is a powerful anti-inflammatory agent that can play a role in both appetite and weight,” Jaffee wrote in an email. “Reduced inflammation in the body helps optimize the performance of the metabolic organs, and fat cells themselves are metabolic organs. Inflamed fat cells do not work properly and can contribute to unhealthy weight gain. “

The Nitro-V study also showed several other changes in the health and well-being of the participants, including many with the potential to affect weight loss. Participants who used the supplement in the study showed a 61% reduction in hunger and had fewer food cravings. In addition, all 37 study participants who took Nitro-V and were classified as prediabetic had their blood sugar levels returned to normal by the end of the 90-day study. The subjects also reported less difficulty resisting food cravings and showed improvements in sleep, happiness, and anxiety. Research also showed that the hemp extract was well tolerated and safe, with blood tests showing that all safety and toxicity levels remained within healthy, normal ranges.

A hemp field in rural Belgium.

getty

While the study was designed to examine the effects of Nitro-V on weight loss, Jaffee says the data suggests the supplement may have other health and health benefits as well.

“The ultimate goal of the study was to identify the overarching power of the ECS system, and the results indicate effects beyond weight loss and appetite suppression,” he writes. “But as with all cannabinoid and ECS researchers today, we still have many unanswered questions about how interactions between cannabinoids and the ECS lead to health improvements.”

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Could CBD Oil Help with Nausea?

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When it comes to the CBD industry, misinformation is rampant. There are too many brands out there trying to make quick money in a phenomenally fast growing market. With a lot of money at stake, these companies are less concerned about what they can do for their customers and more concerned about their profit margins.

The benefits of CBD are known due to the relentless research of dedicated scientists. However, the actions of certain brands lead the general public to remain skeptical.

My advice is to avoid brands that claim that their CBD oil “treats” everything. Unless the cannabinoid is approved by the FDA for medical treatment, no brand is allowed to make any medical claims. However, there is no question that CBD is a potential life changer for many people, for example against nausea. Let’s find out more.

What is nausea?

It is usually classified as a stomach discomfort that makes you want to throw up. It affects a wide variety of people and can have a variety of causes. Common reasons for nausea are:

  • heartburn
  • GERD
  • An infection or a virus
  • Motion sickness
  • Extreme pain
  • Medication

It’s important to remember that nausea is not a disease in itself. Instead, it’s your body’s response to one of a number of conditions. Although it feels awful, nausea is often necessary for your body to fight off unwanted invaders.

Although there are several anti-nausea drugs on the market, there is evidence that CBD may be effective against nausea.

How could CBD help with nausea?

THC is the most common intoxicating cannabinoid found in marijuana. It’s also available in small quantities in hemp. THC is known to create a high, and it binds to endocannabinoid receptors in the brain and spinal cord.

CBD works on these receptors too, but in a different way. First of all, it doesn’t bind directly to the CB1 and CB2 receptors. This helps explain why it doesn’t induce an intoxicating high. CBD helps the body produce higher levels of endocannabinoids like anandamide.

What does the research say?

Currently, much of the research on CBD for nausea is based on people with cancer. Nausea and vomiting are common side effects of chemotherapy. A study published in 2016 examined how cannabinoids can regulate acute and anticipatory nausea. The researchers found that a combination of THC and CBD could provide some relief to cancer patients undergoing chemotherapy.

The American Cancer Society actually puts cannabinoids on its list of drugs to use to treat nausea and vomiting. It suggests that these compounds may be useful in cases where traditional anti-nausea medications are ineffective.

A 2011 review of animal studies also looked at how cannabinoids can regulate nausea and vomiting. The researchers found that CBD was potentially useful against nausea due to its interaction with serotonin receptors. Serotonin is a hormone that affects our mood, behavior, and wellbeing.

THC is potentially more effective at reducing the effects of nausea. However, it causes a high intoxication and is not legal in over a dozen US states. It’s also not legal in many countries around the world. Although CBD is not strictly legal in America, it is widely used and tolerated. It is also widely used around the world, with many nations specifically saying that it is legal.

What types of CBD should I use for nausea?

You will likely get more benefits from CBD for nausea by trying a full-spectrum product. This is because research suggests that the presence of THC might increase its anti-nausea effects. A full-spectrum CBD product contains dozens of compounds and terpenes. However, in the United States, it cannot contain more than 0.3% THC. In the UK, the maximum THC content is 0.2%.

When you feel sick, it makes sense to avoid anything that could make you feel like you are vomiting. While some people can tolerate edibles or oils, others cannot. CBD capsules are another option. They have no taste and are easy to swallow. You could try vaping CBD for a faster effect, but your stomach may not like it!

It also makes sense to start with a relatively low dose and work your way up. Start with 5-10 mg of CBD and increase it as needed.

Final thoughts on CBD for nausea

According to the research available, there is plenty of evidence that CBD could be effective against nausea. While most of the studies are on cancer patients recovering from chemotherapy, you may find that CBD works for your nausea. There are also many other potential benefits of CBD that are worth exploring.

When trying out CBD for nausea, you need to carefully consider your method of consumption. Buy a moderate amount first to see how you react. If you can handle it, you can buy more and possibly increase the amount you consume.

Image by unbekanntuserpanama from Pixabay

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