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Can cocoa consumption help us age better? – Jagwire

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Whether consuming cocoa, which is known to be filled with powerful antioxidants that protect our cells from damage, helps us age better is a question scientists definitely want to answer.

They’re looking for answers in the blood of 600 people age 60 and over who participated in the largest study to date to look at the effects of a cocoa supplement, as well as a common multivitamin, on reducing the risk of heart disease, stroke, cancer, and other health outcomes, says Dr . Yanbin Dong, geneticist and cardiologist at the Georgia Prevention Institute at the Medical College of Georgia.

The COcoa Supplement and Multivitamin Outcomes Study (COSMOS), led by researchers from Brigham and Women’s Hospital and the Fred Hutchinson Cancer Research Center, collected data from 21,444 men and women on the effects of a cocoa extract supplement and / or Multivitamins address general health problems, most of which increase with age.

Dong has just received a $ 3 million grant from the National Institutes of Health to conduct a detailed analysis of inflammatory factors and genetic changes associated with aging to see if cocoa consumption reduces these factors.

Cocoa products have become a “common food” with still growing demand and increasing interest in their antiaging potential, says Dong.

“People think that chocolate is good for you,” says Dong, adding that the global craze for the sweet treat has overtaken the scientific evidence of its human benefit.

Chocolate is widely considered beneficial because it is high in flavanols, antioxidants that are known to produce a powerful anti-inflammatory response. In fact, flavanols are the main ingredient, especially in dark chocolate, and cocoa is a purer form of chocolate, Dong says.

There is no question that flavanols are good for you, the question is how much and in what ways are they good, he says.

While there has been evidence of cocoa’s anti-inflammatory effects in cell cultures, animal models, and even some relatively small human studies, there have not been large-scale randomized controlled trials, scientific studies in which large numbers of participants happen to be in different study arms that include some participants, receiving placebo and / or other treatment, often what is considered the current standard of care.

Dong notes that there is also no solid evidence that multivitamins, the most widely used dietary supplement widely associated with benefits such as reduced cancer risk, are also beneficial.

While he doesn’t deny the biological plausibility that both chocolate and multivitamins should have some health benefit, he says there should be solid scientific evidence behind what we put into our bodies to improve our health.

“We’ll prove it or deny it,” he says, and the scope and duration of the COSMOS test allow him to do both.

Dong and his colleagues will look specifically at aging, including what is known as “inflammaging” and epigenetic aging, both of which are considered good indicators of our biological age. Rather than just looking at the year of birth, biological age also takes into account key factors that affect your function and health, such as genetics and lifestyle. He also has more standard aging measures for these people, such as blood pressure and cognitive function tests.

Inflammation is a major contributor to aging and common conditions such as heart attacks, strokes, Alzheimer’s, and cancer, and “inflammation” has been characterized as a chronic, mild inflammation that is likely to increase the risk of these inflammatory-related diseases.

Epigenetic changes, such as DNA methylation, which can be good or bad and caused by environmental factors, including the foods we eat, are changes in the physical structure of DNA that affect gene expression and ultimately what ours Genes do, including deactivating them. Epigenetic changes are now considered a strong predictor of life and health as well as susceptibility to disease and death, says Dong.

Dong will analyze the levels of key pro and anti-inflammatory factors at baseline and in the first and second years of the COSMOS study in the blood of those who take the cocoa supplement, a multivitamin, both or neither. He will also perform sophisticated, extensive genetic analysis to look for genetic changes that correlate with aging and use “epigenetic clocks” that can calculate biological age based on the amount of DNA methylation.

His work will have the added benefit of better defining the benefits of multivitamins, a top supplement that many only use because they think it’s good for them.

Inflammation can be objectively assessed by measurements such as blood levels of C-reactive protein, a type of biomarker of inflammation made by the liver that can increase dramatically with inflammation. Dong compares the C-reactive protein level that doctors regularly measure with a Geiger counter for the immune response. He will also evaluate levels of tumor necrosis factor alpha, which, as the name suggests, is an inflammatory cytokine that attacks cancer and other invaders, but can be problematic at elevated levels. He will also measure the levels of anti-inflammatory markers such as interleukin-10 or IL-10 and then examine the interaction between the inflammatory response and epigenetic aging, for example whether the genes that regulate IL-10 expression also increase DNA methylation and whether blood pressure goes down, it reduces inflammation, or it changes methylation first.

The researchers’ central hypothesis is that cocoa supplementation reduces epigenetic aging and inflammation, and consequently reduces the risk of cardiovascular disease, the national number one killer, which tends to increase at the age of 65 and older. When they find that the indicators of inflammation and cardiovascular disease are reduced, they want to know if reducing epigenetic changes is driving the improvements.

Dark chocolate in particular is regularly touted for its health benefits as a natural and good source of antioxidants, as well as iron, copper, and other things that are good for your heart and health. Eating chocolate has been reported to lower cholesterol, blood pressure, cognitive decline, and boost the immune response to intruders like the coronavirus, Dong says.

Foods and beverages like grapes and red wine, tomatoes, onions, berries, and peaches are also good sources of flavanols.

Surveys show that the majority of American adults use a dietary supplement, with consumption being higher in women than men and overall consumption increasing with age, according to the Centers for Disease Control and Prevention. Multivitamins are a popular supplement.

Dong’s collaborators on the new studies include the COSMOS main examiners, Dr. JoAnn E. Manson and Dr. Howard D. Sesso of Brigham and Women’s Hospital and Harvard University.

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Women’s Health

This non-profit is closing the gap between women and fertility awareness

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Feminae Vero educates women about the truths of their reproductive health and how it relates to faith.

Mary Kate Knorr did not expect that she would stand up for the unborn child to raise awareness of the fertility of women. But the longer she worked for the cause of life, the more meaningful it made.

“I’ve seen that the pro-life movement hasn’t done enough to address the huge problem we have in our country and around the world with artificial hormonal birth control,” Knorr said in an interview with Aleteia. “That was a big gap for me – and I felt personally called to address it.”

That call led her to found Feminae Vero, a nonprofit dedicated to fertility education and other means of supporting holistic women’s health, with a particular focus on the connection between faith and health. Knorr said “Feminae Vero exists to serve, educate and evangelize girls and women about the truths of their reproductive health and their connection to our Catholic faith.”

Feminae Vero is a new company for Knorr. Her background is in politics and pro-life, and she served for many years as the executive director of Illinois Right to Life. She launched Feminae Vero in January 2021.

Women will find a wide variety of services at Feminae Vero, including the following:

  • Education about fertility
  • Doula services
  • Healing retreats
  • Representation of interests with elected officials and medical professionals

So far, the backbone of their work has been fertility education and it seems that this is the area where the organization can make the greatest impact.

Two projects that are currently in progress are particularly exciting. One of these projects is the creation of a curriculum for middle and high school girls to learn more about their reproductive health and its importance in Catholic education. This curriculum has the potential to be wonderful empowerment and usefulness for girls at an important stage of development.

As Catholics, we know that faith and honest science go hand in hand. ” said Knorr. “It is one facet of our philosophy to go ahead with science to teach girls and women about their bodies and then move on with the truths of faith to ultimately attain evangelization.”

It might seem strange to think that fertility education would lead to evangelization, but Knorr saw a real connection between the two. During her time in the pro-life movement, she made one key observation: “Most of my colleagues who have previously made an election have had a spiritual conversion in addition to their ideological one.” She said.

As they stood up for life, they also became Christians and, in many cases, Catholic. “Abortion is not entirely a logical problem,” said Knorr. “It’s a heart problem too.”

The second project is a curriculum for seminarians and clergy. “A future goal is to develop a program for seminarians and clergy that enables them to better support girls and women from a ministerial point of view”, said Knorr. This project sounds like a critical force for good: sometimes there is a discrepancy between what the church teaches about women’s health and what local clergy understand about that teaching, so this project will help bridge that gap to bridge.

There are many things in the life of modern women that are physically and spiritually toxic. Knorr hopes Feminae Vero will be a refreshingly holistic and positive resource.

“One of my main goals in founding Feminae Vero was to offer women a healing hand.” She said.

There are so many voices in society today who have deeply hurt women by lying to them about their origins and God’s plan for their bodies. Through our healing retreats and the service and education we want to offer women, our goal is to take women by the hand and initiate them into a healing process.

Ultimately, that healing comes from Christ. “It is the Lord who does the healing,” she explains.

That is why we place so much emphasis on evangelization as the primary goal. We believe that when shared with prayer and compassion, the truth leads women to Jesus Christ – and once they meet the Lord, their healing will be inevitable.

Knorr wants women to know that God created them with profound purpose and purpose. “The objectification and abuse of women in our culture is a result of human decline,” she explains, “but the theology of the body of John Paul II tells us that we are meant for more.”

Her goal for Feminae Vero is to help women discover that purpose and intention. She says, “Women can find such immense healing in the arms of Jesus Christ.”

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Women’s Health

Task force tackles problems that slow women’s success in workforce | Business News

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Cora Faith Walker, Chief Policy Officer of St. Louis County Executive Dr. Sam Page, speaking at a community meeting on Tuesday. September 14, 2021. She leads the advancement of the District Board’s political priorities by providing an integrated approach to policy development and external engagement.



Childcare. Wage gaps. Education. Health care.

These topics were included during a town hall in Florissant on Tuesday, September 14th, to gather input from local women on topics and factors preventing them from fully participating, moving forward, or being successful among the workforce.

The lunchtime event was organized by United Women’s Empowerment (United WE) and the Missouri Women’s Economic Development Task Force at the city’s Civic Center.

Wendy Doyle, United WE CEO, said the organization is hosting a number of these town halls across the state to provide policy recommendations to leaders and lawmakers that will be sent to them in late 2021.

She said her organization’s goal is to collect the qualitative data from women to link it to quantitative research on working women in Missouri. Some of this data includes statistics such as that 44% of all Missouri counties have no recognized childcare facilities and that of the total Missouri women population, 15.4% are below the poverty line, compared with 12.9% of men. The organization also found that 18% of Missourians living in poverty were under 18 years of age.

Wendy Doyle, United WE CEO, said

“Above all, we wanted to have informed conversations as we approach the pandemic recovery because we know women have been severely affected.” Wendy Doyle, CEO of United WE, called. “And we just want to hear their stories.”

Dawn Gipson, Diversity Director at Centene, spoke during the small group sessions about how the pandemic is doing for their truly enlarged women lifting heavy loads both outside and inside the home. She also noted that people may be scared of going back to work after working from home for over a year.

“So there is this fear of going back to the office, but the focus is on ‘We need to get back to normal,'” she said, noting that women and people of color may not want to interact on a daily basis with people who are not tolerant or respectful of people’s identity.

Cora Faith-Walker lives in Ferguson and is Chief Policy Officer of the St. Louis County Executive’s Office. She agreed with Gipson and said the shutdown was so much more than just a shutdown.

“People think we can just snap our fingers and go back to 2019,” she said, adding that she almost felt like she forgot how to small talk while working remotely Office involved.



Dawn Gipson

Dawn Gipson



Finally, the small groups ended their conversation for a full group discussion that addressed the main barriers encountered during the small discussions: access to affordable childcare; same salary; Access to adequate health care; Access to equity; Teach children at home or help with their virtual education; and try to keep the household together even when working outside the home.

“Above all, we wanted to have informed conversations as we approach the pandemic recovery because we know women have been severely affected,” said Wendy Doyle, CEO of United WE. “And we just want to hear their stories.”

United WE’s November report said that due to the decline in the industry during the COVID-19 pandemic, Missouri could potentially lose 48% of its childcare offering, meaning there is only one place available in a licensed daycare for six children.

Faith-Walker later addressed the challenges faced by the county executive in obtaining pandemic aid to childcare providers.

“Another type of challenge we had with vendors was probably the amount of technical support that was sometimes required to take advantage of opportunities like the PSA programs,” she said.

The organization held two talks before Tuesday – one in Joplin and one in Sedalia. Several others are planned, including October 6 in Kansas City; October 14 in Kirksville; and October 28th, held virtually, and will highlight the needs of women of color.

For more information or to register, visit united-we.org/mo-town-halls.

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Women’s Health

Notts dad created emotion posters and wrote book after son suffered mental health problems during pandemic

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A father of three from Nottingham has set a goal of raising £ 10,000 this year to buy Christmas gifts for cared children.

David Rogers, 50, first started his charity mission when his son suffered from mental symptoms during the pandemic and felt he wanted to do something to help other children who have no one to talk to.

The designer, who lives near Newark and owns a shop in Nottingham city center, first set out to create emotional posters to help young people open up.

David Rogers has his own children’s book “Have You Heard of Jelly Bean Juice? to raise money for children in care

“During the pandemic, our son Milo, who is 10 years old, had some mental health problems,” explains David.

“He was able to open up to me and we got support, but I thought of other children who may not be able to speak easily, or their parents who, through no fault of their own, are not.” sure how to communicate about these things.

“We set out to research and design posters that would help children point to the faces that are sad or angry, that most reflect their feelings, just to start a conversation.

“We sold them to raise some money for charity, but we also gave them away to schools, parents, teachers and children.

“They have had a storm and we have had really great feedback on how they have helped kids get into conversation, even if it’s the smallest kind, it’s a start and hopefully it will make a difference.

“We have now also made posters for teenagers.”

David and his company created posters to help children identify their emotions and speak

David and his company created posters to help children identify their emotions and speak

David’s charity efforts began a few years ago when he decided to raise money for children in social institutions on Christmas Day. He would get their Christmas lists and go to work raising the money to fulfill them.

Last year he was able to help three homes, but this year he has bigger ambitions and has published his own children’s book to pay for Christmas gifts in 10 different children’s homes.

“For the past 4 years I have tried to give children a wonderful Christmas Day in social institutions. They are asked to give me a list of how lucky most children are, and then I use the money to buy gifts. We also use whatever is left to help blackboards, women’s shelters and gifts, toiletries and groceries in the run up to Christmas.

“I helped a children’s home for the first three years, last year I managed to help three, but this year my dream is to help ten.”

To achieve his goal, David needed a plan – and then he remembered a children’s story he had written that languished on his laptop.

“I wrote the story for my son for fun, but I’m a designer, not a writer, so I’ve never done anything with it,” says David, who is also the father of Lewis, 16, and Charlie, 6.

“But when I was thinking about how to raise money, the book seemed like a good idea because I knew I could have it designed and printed through my business, keep everything local, and not pass these costs on.

“It has been produced to a really high standard, is beautifully illustrated and printed in Nottingham, and every single penny that is raised goes straight to the charity campaign.”

The book, Have You Heard of Jelly Bean Juice? was inspired by bath times with his son when they mixed up different hand washes, resulting in strange and wonderful colors and a mixture that smelled like jelly beans.

Ever heard of Jelly Bean Juice?  Is for sale to raise money for cared children this Christmas

Ever heard of Jelly Bean Juice? Is for sale to raise money for cared children this Christmas

“It’s a bit of fun with a group of animal lovers at the center of a party, including a Siberian moose named Bartholomew. At one point an accident happens and jelly bean juice is spilled all over the place. Then jelly bean juice is created and one of the guests decides Mindy, whose father’s name is Mr Big Shot, that they can market and sell it. “

David and his wife Annabelle have been selling the books through word of mouth and their Instagram accounts for two months and have already raised £ 6,500.

But David wants to hit his £ 10,000 goal by the end of November.

“I firmly believe that these children can have the same experiences at Christmas as other children and I want to help more,” he says, a crucial time for women fleeing their homes with children. We will also support boards and, if possible, charities for the homeless. “

David’s wife Annabelle, who is also a designer, has supported him with all aspects of publishing and selling the book through her popular Instagram account @designermumetc and David himself can be found at @shopperdave_.

The book costs 8 pounds including postage and packaging and is already on its way all over the world.

“We got two orders from Florida, that’s great, and we’ve now sold around 300 books in total.

“It was very important to me to create something good quality so that for a charity donation people would get a really nice product and so far the buyers seem to love the book which is a good feeling.

“But it will feel better when I reach my goal and can give these children a Merry Christmas in 10 social institutions. That is the most important thing.”

As part of their charity work, David and his company also produce luxury tea towels with maps of popular UK vacation destinations such as North Norfolk, and they also sell the Emotions posters for children and teenagers.

Have you heard of Jelly Bean Juice? Go to Instagram and send a message to @designermumetc or @shopperdave_

Or send an email to david@wearepure.net

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