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Does It Have an Effect?

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High blood pressure or high blood pressure can lead to serious health problems like a heart attack or stroke. But because high blood pressure doesn’t usually cause symptoms, many people don’t even know they have it. This is why it is so important to check your blood pressure regularly.

If you have high blood pressure, you may have heard that cannabidiol (CBD) can help lower blood pressure. Here’s what the research says plus tips on how to find a few products to explore.

Blood pressure is defined as the pressure of blood against the walls of the arteries. While it is normal for blood pressure to go up and down over the course of a day, persistently high blood pressure levels are a problem.

There are two types of high blood pressure:

  • Primary hypertension is the most common. It develops gradually for no apparent cause, but it may be related to genetics, physical changes in the body, or being high in body weight.
  • Secondary hypertension comes quickly and can be more serious. It has a number of causes, including kidney disease, congenital heart defects, thyroid problems, alcohol use, and certain drugs and stimulants such as cocaine and amphetamines.

Because high blood pressure is often a silent condition, symptoms may not appear until the severity of the condition develops. At this point, symptoms can include:

  • headache
  • Nosebleeds
  • shortness of breath
  • dizziness
  • Chest pain
  • Flushing
  • Changes in vision
  • Blood in the urine

If you have these types of symptoms, it is important to see a doctor right away.

CBD is one of the active ingredients in the cannabis plant. In contrast to tetrahydrocannabinol (THC), it has no intoxicating properties or creates a “high”. Instead, there is a lot of focus on the potential therapeutic benefits of CBD. It can be helpful for everything from pain relief and improved sleep to anxiety and even addiction.

CBD is available in a few different types: full spectrum, broad spectrum, and isolate.

While full-spectrum and broad-spectrum both contain other compounds from the cannabis plant – like flavonoids, terpenes, and other cannabinoids – full-spectrum CBD is the only type that has some THC in it (usually less than 0.3 percent).

CBD isolate is pure CBD. However, it’s important to know that any type of CBD can contain traces of THC that could be detected in a drug test.

These three forms of CBD are made into a wide variety of products, including:

  • Oils and tinctures. These liquids have been fortified with CBD. You can either place them under the tongue or add them to food and drinks.
  • Edibles. Sometimes CBD is added to foods like gummy bears or beverages like teas. Edibles are one of the most popular methods of consumption because they are discreet and easy to dose.
  • Capsules. CBD can be taken in tablet or capsule form.
  • Subjects. Topical CBD is applied directly to the skin for targeted relief.
  • Vape juices. These products are designed to be inhaled with a vape pen. The effects are very quick, but there have been reports of lung injuries related to vaping. Currently, we don’t know if vaping CBD carries the same risks.

CBD interacts with the body’s own endocannabinoid system (ECS), a complex system that helps regulate a number of processes in the body.

As our understanding of the ECS continues to evolve, we know that it has three components:

  • Endocannabinoids, which are molecules that are made in the body
  • Endocannabinoid receptors found throughout the body; the main receptors are called CB1 and CB2 receptors
  • Enzymes that break down endocannabinoids once they have finished their function

Currently, researchers believe that the main role of the ECS is to maintain homeostasis in the body. The ECS is associated with a number of processes in the body, including:

  • Appetite and digestion
  • metabolism
  • pains
  • mood
  • sleep
  • Engine control

Cannabinoids, including THC and CBD, interact with the ECS by attaching to receptors in the same way as endocannabinoids.

While THC can bind to both CB1 and CB2 receptors, researchers don’t yet understand how CBD interacts with the ECS. One theory is that CBD prevents endocannabinoids from breaking down and gives them greater effects on the body. Another theory is that CBD binds to a receptor that researchers have not yet identified.

There is research from 2011 suggesting that ingesting both THC and CBD along with the other compounds in the cannabis plant may be more effective than using a single cannabinoid on its own. This theory is known as the entourage effect, and this is why some people say that full-spectrum CBD works better than broad-spectrum or isolate.

There is some evidence that CBD products might help lower blood pressure, but the research is somewhat contradicting.

A 2017 study of nine male participants found that a single dose of CBD in healthy participants lowered blood pressure in those at rest and those who were under stress.

Another 2017 study in mice found that CBD significantly reduced stress-related increases in blood pressure and heart rate.

However, a 2020 study in rats found that CBD was not effective in lowering blood pressure, despite having antioxidant effects. Another 2020 study was more promising, the results of which showed that CBD could lower blood pressure in stressed patients.

Researchers recognize the beneficial effects of CBD in cardiovascular disease, but note that additional study is needed to fully understand how it could help.

Both the Food and Drug Administration (FDA) and the World Health Organization (WHO) recognize the potential benefits of CBD.

A report by the WHO from 2017 describes CBD as generally well tolerated with a good safety profile and no effects that could indicate a potential for abuse or dependence.

The FDA notes that more research is needed and notes that many questions about the safety of CBD remain unanswered. In addition, it should be noted that some CBD products are inaccurately labeled and of questionable quality.

If you decide to give CBD a try, be aware that some people experience side effects, including:

  • diarrhea
  • Changes in weight or appetite
  • fatigue

2012 research on cannabinoids and anxiety suggests that some cannabinoids can have two-phase effects, meaning that they have different effects depending on the dose taken.

Specifically for high blood pressure, a 2011 study found that THC alone or in combination with CBD sometimes increased blood pressure and sometimes decreased it.

Finally, it’s important to keep in mind that CBD can interact with some drugs, including those used for high blood pressure. If you are considering using CBD to treat high blood pressure, speak to a doctor first.

Although CBD comes in many forms, the best option for high blood pressure is likely to be an oil or tincture rather than a topical or edible one. Oils tend to offer higher bioavailability, which means a higher rate of absorption for greater effectiveness. Sublingual products also have a full body effect.

The FDA does not regulate CBD products in the same way as diet supplements and medications, which means consumers need to be careful about the brands they use. To find a high quality CBD product, there are a few things that are important to check.

Certificate of Analysis

Avoid buying CBD products that don’t have a Certificate of Analysis (COA). A current COA means that a product has been tested for safety and purity by an external laboratory. Many brands make these reports available through a QR code on the product packaging or on the website.

When you review the COA, double-check that the amount of CBD and THC the lab found matches the advertised. Also, look at the pollutant test results to make sure there are no unsafe amounts of pesticides, heavy metals, or mold.

Warning letters and lawsuits from the FDA

When a CBD company makes unaudited health claims, the FDA sends out a warning letter. You can check online whether a company has received such a letter and whether it has been involved in any litigation. If you find that a company received one, it might be best to avoid it.

Customer rating

Look for customer feedback on both the company and the product you are considering to get an idea of ​​its effectiveness. However, be aware that some brands:

  • only publish positive reviews on their pages
  • Remove reviews mentioning specific health conditions to comply with FDA regulations

transparency

Always read a brand’s website that you’re interested in. Some brands will be very open about where they get their CBD from and how they make their products. These are the brands you will want to buy from.

Don’t rely on CBD alone to lower blood pressure. It is important to speak to a doctor and follow their prescriptions. This can include medication.

There are also home remedies that can help treat the condition. Eating a nutritious diet high in fruits, vegetables, whole grains, and lean proteins is important, as is weight control and regular exercise. It is also recommended that you maintain a low-sodium diet.

Coping with stress is also important. Things like meditation, massage, yoga, and even deep breathing are worth exploring to relieve stress.

Finally, smoking can also affect blood pressure. Chemicals in tobacco smoke damage tissues in the body and harden the walls of blood vessels. Alcohol can also increase blood pressure, so limiting consumption can be helpful.

Before trying CBD for treating high blood pressure, it is important to speak with a doctor. Regular checkups are also a good idea, as symptoms of high blood pressure often don’t show up until the condition becomes more severe.

If you experience symptoms or if you can’t remember the last time your blood pressure was measured, it’s a good idea to speak to a doctor.

High blood pressure can be dangerous, and it’s a condition that may not be noticeable until it’s serious. Fortunately, there are medications and lifestyle changes that can help, and there is some evidence that CBD is another option worth exploring. Before doing this, however, consult a doctor.

Jessica Timmons has been a freelance writer since 2007, and covers everything from pregnancy and parenting to cannabis, chiropractic, stand up paddling, fitness, martial arts, home decor and much more. Her work has appeared in mindbodygreen, Pregnancy & Newborn, Modern Parents Messy Kids and Coffee + Crumbs. Check out what she’s doing at jessicatimmons.com.

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Synchronicity Wellness – Boulder Daily Camera

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Synchronicity hemp oil

Hemp oil may seem like a recent trend, but boulder-based synchronicity has been in business for over two decades.

Hemp oil may seem like a recent trend, but boulder-based synchronicity has been in business for over two decades. With products 100% grown and hand-processed right here in Colorado, the company strives to keep it local – and share the profound benefits of full-spectrum hemp oil.

Twenty years in the making, Synchronicity has worked to perfect the only hand-pressed hemp oil on the market. The oil comes directly from patent-pending gold standard crops grown on the banks of the Arkansas River in Colorado.

A gentle hand pressing process leads to the highest quality. “We’re proud to offer the most nutrient-dense, full-spectrum hemp oil on the market that helps people achieve more balance than just CBD alone can provide,” said Andrew Campbell, CEO of Synchronicity. “We have set the standard for the highest quality, full-spectrum hemp oil products that you can find anywhere.”

Tireless innovation
Synchronicity knows the proof lies in the feedback they get from real people on a daily basis: faster recovery, better sleep, and less stress.

“We’re always researching and innovating to improve every step of our process,” says Campbell. “We have put our heart and soul into our patented plant genetics, hand press and patented infusion process so that you can really feel the full effect that your body and mind deserve.”

Your hard work has paid off.

The evidence of this is a bold achievement: most third-party certifications in the industry. “We pride ourselves on our unparalleled list of certifications,” says Campbell. “Synchronicity was founded with a compliance-first approach and continues to be committed to setting standards and making the highest quality hemp products for both people and trading partners.”

NextGen wellness pioneers
With innovation as a constant motivator, Synchronicity recently partnered with the University of Colorado Athletics to further build the future of Colorado – the next generation of nature wellness pioneers. “Synchronicity and CU share a natural and soulful connection with the mission for health and wellbeing,” says Campbell.

CU Athletics’ WHOLE (Wellness Health Optimal Life Experience) approach aims to support and develop student athletes in the fields of academics, sports nutrition, sports training, medical services, mental health, and leadership and career development. Synchronicity’s innovative products support this mission.

“Our partnership helps CU Athletics continue to provide a holistic, premium experience for student athletes in all sports,” said Campbell. “As a Colorado-based company on a mission to advance wellbeing, we are excited to partner with CU Athletics. Working with an organization that shares our values ​​and our passion for innovation and leadership is of the utmost importance to us. “

CBD vs. hemp?
One of Synchronicity’s most important training points is explaining the difference between CBD and hemp. It can be confusing.

However, Campbell says it’s a simple science: “A hemp plant is loaded with dozens of cannabinoids, terpenes, bioflavonoids, omegas, nutrients and minerals that work together to get the full benefits of pain relief, muscle regeneration, better sleep, anxiety relief, and more. “

Synchronicity has shaped the True Entourage Effect ™: To give the body the power of the whole plant – exactly as nature intended. “CBD is just a compound that has been isolated and extracted from the hemp plant, away from all of its sister elements,” says Campbell. “This reduces the full and natural strength of the plant. As the saying goes: ‘The whole is more than the sum of its parts.’ “

Popular categories: pain, sleep, stress, skin care

Since the entire plant produces the True Entourage Effect ™, it follows that hemp oil can have a wide range of uses. “Because full-spectrum hemp oil interacts directly with and balances the body’s complex and far-reaching endocannabinoid system, there are seemingly endless reasons why people choose to ingest hemp oil,” says Campbell. “Simply put, our plants help the body reduce inflammation and balance this system, which is why this plant has so many different benefits.”

There are many reasons people turn to Synchronicity products, but the most sought-after ones right now are relief from pain, sleep, stress, and skin care issues. “Our line of products is tailored to meet individual needs and an active lifestyle 24 hours a day,” explains Campbell.

A wide range of topical and ingestible products – including a helpful test kit option – offer consumers a variety of ways to find out which method of administration is best for their body. This is important, says Campbell, “because hemp oil is definitely not a universal product.”

Synchronicity constantly educates and informs about the best way to personalize its hemp products by following the work of Synchronicity President Dr. Steven Kraus shares, who has been successfully treating patients in his own practice for over three decades. Consumers can find scientific and educational articles on the Synchronicity blog.

“Our goal is to better inform everyone about the right dosage, products, methods and history related to hemp,” says Dr. Kraus. “And since every human body is different, our approach is simple: we ask our consumers the right questions, listen to their needs and make suggestions based on our many years of experience and expertise.”

In fact, the company offers free 30-minute consultations with hemp experts that can be arranged directly through the website.

What’s next?
So what do you do with a company that is already a leader in its category? Deeper.

“Our goal is to educate and strengthen every single person who crosses our path with knowledge and awareness of the life-changing benefits of hand-pressed full-spectrum hemp oil and its ability to harmonize mind and body.”

It’s all part of a larger movement that gives people the ability to heal themselves naturally rather than using chemicals and drugs, Campbell explains. “We hope that we will offer support and lead people away from harmful chemicals – and back into a healthy relationship with nature.”

More information is available at www.synchronicityhempoil.com.

Photos courtesy of Synchronicity Hemp Oil

Synchronicity hemp oil

Synchronicity hemp oil

A wide range of topical and ingestible products – including a helpful test kit option – offer consumers a variety of ways to find out which method of administration is best for their body.

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CBD for Vertigo: Research and Side Effects

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It can be unsettling to experience dizziness, a feeling that the world is spinning around you. Severe dizziness can even affect your ability to complete everyday tasks as it upsets your balance. Something as harmless as standing up too quickly can make you dizzy due to a rapid drop in blood pressure.

However, dizziness is not a requirement. Instead, it’s a symptom. It can occur due to underlying conditions like multiple sclerosis or problems with the inner ear. Certain medications can also make you feel dizzy.

Treatment for dizziness depends on the cause. You might be interested in home remedies or even natural substances like cannabidiol (CBD).

In this article, we take a closer look at CBD, whether it can help with dizziness and possible side effects. We will also review dizziness treatments and report on when to see a doctor for dizziness.

CBD comes from the cannabis plant. It has several potential health benefits, including insomnia and pain relief.

CBD is similar to another cannabinoid called tetrahydrocannabinol (THC), but it doesn’t produce the same “high” THC.

You can find CBD in many forms, including:

People looking for a full body effect to relieve conditions like chronic pain and insomnia should stick to ingested products like oils, gums, and capsules. Topicals are a better option for targeted pain such as joint pain.

There are also several types of CBD:

  • Isolate. This is pure CBD and contains only CBD.
  • Broad spectrum. Broad-spectrum CBD contains some cannabis compounds (like other cannabinoids) but no THC.
  • The whole spectrum. Full-spectrum CBD contains some THC (less than 0.3 percent for federally legal products) and countless other cannabis plant compounds such as terpenes, flavonoids, and other cannabinoids.

Research suggests that CBD works better when combined with THC, which is why a full-spectrum product is more beneficial than an isolate. This is known as the entourage effect.

However, if you want to avoid THC, you would be better off with an isolate or broad spectrum product. Note, however, that any type of CBD can contain traces of THC, which can be detected in a drug test.

CBD is unlikely to help with dizziness. However, it can help with related symptoms like nausea.

Animal studies from 2016 showed that CBD reduced nausea in rats, while human studies in people undergoing chemotherapy showed that a combination of CBD and THC can help with treatment-related nausea.

Still, the available research on CBD and nausea focuses primarily on chemotherapy-related nausea rather than vertigo-related nausea.

If you are dizzy, it is possible that CBD will make you feel dizzy. Some research on cannabis (including THC and CBD) suggests dizziness as a side effect.

Another 2020 study of people undergoing chemotherapy found that although THC and CBD worked together to reduce nausea and vomiting, 31 percent of participants experienced moderate or severe dizziness, disorientation, or sedation.

There is also research that CBD can lower blood pressure, which could potentially make dizziness worse.

A 2017 study found that participants who took 600 mg of CBD had lower blood pressure than the placebo group. However, the study was very small with only nine male participants.

The World Health Organization believes it is safe to take CBD. But it is possible to experience mild side effects like:

  • Appetite changes
  • Weight changes
  • fatigue
  • diarrhea

Despite the short list of side effects, it is important to speak to your doctor if you are on any medication and consider taking CBD. It is possible for CBD to interact with certain drugs, such as those with a grapefruit warning on them.

While the Food and Drug Administration (FDA) sends warning letters to CBD brands that misrepresent or mislabel their products, the organization does not regulate CBD products in the same way as prescription drugs.

This means that not all CBD products are safe to consume as they may not contain what the label says.

A 2021 study that looked at poison control center cases between 2019 and 2020 found that reports of products containing CBD were on the rise. Reported side effects from these cases are dizziness, dizziness, and nausea. Researchers suggested that this surge could have something to do with inaccurate or fraudulent labeling of CBD products.

For this reason, when choosing CBD, it is important to contact a company that has products tested by a reputable third-party laboratory and provides up-to-date Certificates of Analysis (COAs).

Treatment for dizziness typically depends on the underlying medical condition that is causing the dizziness. For example, if medication is causing your dizziness, your doctor may recommend a different one.

Treatment also depends on the type of vertigo you have.

  • Peripheral vertigo. Peripheral vertigo is caused by a problem with your inner ear that is responsible for your balance.
  • Central vertigo. Central vertigo affects your brain.

Depending on the type and cause, your doctor may recommend the following:

  • Drugs for acute dizziness
  • Exercise or physical therapy to improve balance (for people with permanent inner ear diseases)
  • Avoid dizziness triggers
  • surgical treatment (only as a last resort)

In people with benign positional vertigo, twisting the head (like the Epley Maneuver) can help reposition calcium deposits that can cause problems in the inner ear.

It’s time to see a doctor for dizziness if:

  • does not go away
  • happens frequently
  • happens with other symptoms, such as:
    • Loss of consciousness
    • Vision problems
    • fever
    • Tingling or weakness in your body
    • slurred speech
    • Trouble walking
    • Chest pain

There is no evidence that CBD can help with dizziness. In fact, it can make dizziness worse in some people.

If you have frequent attacks of dizziness, you should speak to your doctor. It can be a sign of an underlying condition that needs treatment.

Is CBD Legal? Hemp-derived CBD products (containing less than 0.3 percent THC) are legal at the federal level, but are still illegal under some state laws. CBD products derived from marijuana are illegal at the federal level, but legal under some state laws. Find out about the laws of your state and wherever you travel. Keep in mind that over-the-counter CBD products are not FDA approved and may be inaccurately labeled.

Steph Coelho is a freelance writer with chronic migraines with a particular interest in health and wellness. If she’s not clicking on her keyboard, she’s probably stuck in a good book.

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Lung Cancer Shrinks in Patient Using CBD Oil

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One case report describes the dramatic shrinkage of a tumor to a quarter of its original size in a non-small cell lung cancer (NSCLC) patient who refused conventional treatment, continued smoking, and later revealed that she was taking cannabidiol (CBD.) Oil.

The patient was an 80 year old woman.

At diagnosis, the tumor measured 41 mm and there was no evidence of local or further spread. Therefore, it was suitable for a standard treatment regimen consisting of surgery, chemotherapy, and radiation therapy, the authors note.

The patient refused conventional treatment. She was monitored every 3-6 months with regular CT scans.

After 2.5 years, the CT scans showed that the tumor had shrunk to 10 mm.

The patient then announced that she had taken CBD oil, which was suggested by a family member. It was taken orally about two to three times a day.

Details of the case were published in BMJ Case Reports on October 14th.

“We are aware of the limitations of this case report,” write the authors, directed by Kah Ling Liew, MD, of Watford General Hospital, Watford, UK.

“Although there appears to be a link between ‘CBD oil’ ingestion and the observed tumor regression, we cannot conclusively confirm that tumor regression was due to the patient’s ingestion of ‘CBD oil’,” they comment.

The team also notes that there are similar case reports in the medical literature.

Both points were highlighted by experts who responded to the publication via the UK Science Media Center.

“This is one of many promising individual case reports of medical cannabis self-treatment in various cancers,” said David Nutt, DM, FRCP, FRCPsych, Edmond J. Safra Chair in Neuropsychopharmacology, Imperial College London, London, United Kingdom. “Such case reports are biologically credible given the adaptogenic nature of the endocannabinoid system.”

He noted that “a case report alone is not enough to prove that one caused the other – we need studies for that. There are already some controlled studies out there and more are needed to understand the potential of medicinal cannabis in a number of cancers. “

Another expert, Edzard Ernst, MD, PhD, Professor Emeritus of Complementary Medicine, University of Exeter, Exeter, UK, pointed out that cannabinoids have reduced the size of prostate cancer tumors in animal models. “Previous case reports have shown encouraging results in human cancers as well,” he noted. He also said that more studies are needed.

“Case reports cannot be considered reliable evidence, and there is currently no data from rigorous clinical studies to suggest that cannabis products alter the natural course of cancer,” Ernst said.

Patient declined recommended treatment

The patient initially presented with a persistent cough that did not heal with antibiotic therapy. She has a history of mild chronic obstructive pulmonary disease, osteoarthritis, and high blood pressure. She is a current smoker with a 68 year history of smoking. She has no history of alcohol consumption and is taking several prescription drugs.

After an initial CT examination, she was given a CT-guided lung biopsy and diagnosed with NSCLC (TNM stage T2bN0Mx). Further analysis of the tumor tissue showed that it was negative for ALK and EGFR mutations. PDL1 was expressed by <1% of the tumor cells. No distant metastases were found.

A subsequent CT scan showed that the main tumor in the right median lobe had shrunk from 41 mm to 33 mm. There were new bilateral nodules in the upper lobe, one in the left apex measuring 4 mm and one in the right apex measuring 6 mm.

The patient was referred to a cardiothoracic surgeon for a possible lobectomy, but the surgeon refused to undergo surgery. She was then referred to the oncologists. She underwent repeated CT and positron emission tomography (PET) scans, which showed that her cancer had further shrunk. The CT showed a reduction of 11 mm and the PET a reduction of 18 mm. The left apical knot had resolved and the right superior lobe knot was reduced in size.

The patient was offered stereotactic ablative radiation therapy, which she refused. Since she had refused all standard therapies, it was decided to “watch and wait”. The patient was subjected to regular CT monitoring.

The tumor continued to regress over the course of 2.5 years. By February 2021, it had shrunk to 10mm, an overall reduction of 76% of the maximum axial diameter. The average reduction rate during the observation period was 2.4% per month.

“This case was brought to the attention of the local pulmonary MDT [multidisciplinary team] in February 2019 when serial imaging showed a reduction in tumor size despite not receiving conventional treatment for her lung cancer, “the authors write.

The patient was contacted to discuss her results. She announced that she was using CBD oil and had started taking it in August 2018. No changes were made to her prescription medication, diet, or lifestyle, and she continued to smoke a pack of cigarettes each week.

“I wasn’t very interested in traditional cancer treatments,” said the patient, “because I was concerned about the risks of surgery and I saw my late husband suffer from the side effects of radiation therapy. My relative suggested that I try cannabidiol should (CBD) oil “to treat my cancer, and I’ve been taking it regularly ever since. I am overjoyed that my cancer is shrinking, which I think was caused by the “CBD oil”. I can take it very well and I intend to do this treatment indefinitely. “

The source of the CBD oil was outside of the UK. According to their supplier, the main active ingredients were Δ9-tetrahydrocannabinol (THC) with 19.5%, CBD with 20.05% and tetrahydrocannabinolic acid with 23.8%.

“The product this patient was using was reported to be high in THC (the intoxicating component of cannabis) and from outside the UK,” commented Tom Freeman, PhD, Senior Lecturer and Director, Addiction and Mental Health Group, University of Bath. Bath, UK. “This type of product is very different from most CBD oils, which contain mostly CBD. Unlike prescription drugs, CBD wellness products lack guarantees of quality, safety, or effectiveness and should not be used for medicinal purposes. “

The authors have not disclosed any relevant financial relationships. Nutt chairs the scientific committee of the Drug Science charity, which receives unrestricted educational grants from some medical cannabis companies. Ernst and Freeman have not disclosed any relevant financial relationships.

BMJ Case Rep. 2021; 14: e244195. Full text

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