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CBD Oil, Are the Benefits Claimed Too Good To Be True? – Cleveland Clinic



Today, many of us could certainly choose a miracle cure, especially those of us struggling with chronic pain, overwhelming anxiety, cancer-related symptoms, and / or difficult-to-treat neurological conditions. So it’s no wonder that CBD oil shows up in our search results. But can we really rely on CBD oil to affect our symptoms as positively as we’d hope it would? Internal medicine specialist Paul Terpeluk, DO explains why CBD oil may not be as effective as we’d like it to be.

The Cleveland Clinic is a not for profit academic medical center. Advertising on our website helps support our mission. We do not endorse non-Cleveland Clinic products or services. politics

What is CBD?

CBD, or cannabidiol, is just one of more than 100 chemical compounds found in the cannabis sativa plant. But it’s THC (tetrahydrocannabinol), not CBD, which is the main psychoactive compound in cannabis that gives you a euphoric high.

CBD is made from hemp, a cannabis plant that is very low in THC so you won’t get high. CBD oil is simply a product that contains CBD extract and an oil like coconut oil, typically for topical use.

It’s important to know that since the implementation of the 2018 Farm Bill, the manufacture and sale of CBD products in the U.S. has been legalized at the federal level as long as they contain less than 0.3% THC. However, it is still illegal under some state laws.

In addition, Dr. Terpeluk that the market is oversaturated with CBD products – from bath bombs to gums, lotions, creams, tinctures, and oils – none of which are Food and Drug Administration (FDA) approved and may not be 100% pure CBD. As of mid-December 2021, the FDA has only approved one cannabis-derived and three cannabis-related products, all of which are safe to obtain with a prescription from a licensed healthcare provider.

“Most CBD products are not subject to supervision by a regulatory authority,” says Dr. Terpeluk. “Most of the CBD you buy is most likely contaminated with other cannabinoids, including THC, unless there is a strict marketing campaign and quality control that says it is 100% CBD oil.”

What are some of the benefits of CBD?

However, several studies show that the benefits of pure CBD can have far-reaching positive effects. To understand these benefits, it is important to consider our body’s endocannabinoid system, a complex system of enzymes, neurotransmitters, and receptors that play an important role in the development of our central nervous system. This system helps regulate a wide variety of functions, including pain, motor control, memory, appetite, inflammation, and more. By further studying the effects of CBD in these specific areas, we can better understand how CBD affects a wide variety of diseases and disorders.

Helps with neurological diseases

The FDA has approved Epidiolex for the treatment of several seizure disorders, including two rare conditions known as Duvet syndrome and Lennox-Gastaut syndrome. Several case studies suggest that CBD can also be beneficial for patients who are resistant to anti-epileptic drugs. “In epilepsy, there is a threshold in your brain and you have a seizure,” says Dr. Terpeluk. “CBD raises that threshold.”

Other studies suggest that CBD may also be useful in treating symptoms of multiple sclerosis, Parkinson’s, and Alzheimer’s because it has neuroprotective, anti-inflammatory properties. However, more studies are needed as many suggest that not just CBD alone, but a combination of CBD and other cannabinoids can help alleviate many of these symptoms.

It can help with pain relief

By interacting with neurotransmitters in your central nervous system, CBD could potentially relieve pain related to inflammation, arthritis, and nerve damage (peripheral neuropathy). In a four-week study, people with nerve damage in the lower half of their bodies reported a significant reduction in intense, sharp pain after using a topical CBD oil.

“All of our various painkillers affect part of our pain system, be it Tylenol®, Aspirin®, morphine or opioids,” explains Dr. Terpeluk. “Nobody wants to be addicted to opioids. So if you can take a cannabinoid that is not addictive but can suppress pain, that would be the holy grail of chronic pain. “

Still, he warns, there is still much more research to be done, including whether CBD has significant long-term adverse effects when used for pain relief.

“If you take it unregulated, you don’t know how much is in and you are not exactly sure how it affects you outside of your specific pain,” says Dr. Terpeluk.

It can help with anxiety and mood disorders

Anxiety and mood disorders such as depression or post-traumatic stress disorder can seriously affect your daily life and often cause both physical and emotional stress, which can lead to other underlying conditions such as insomnia, high blood pressure, chronic pain, and heart disease. It is too early to understand the full range of effects of CBD on anxiety and mood disorders, but individual studies seem to indicate different positive results. In a study of 57 men who received either oral CBD or a placebo 90 minutes before taking a simulated public speaking test, the researchers found that a 300-mg dose of CBD significantly reduced social anxiety during the test.

And while there are a variety of treatments for anxiety and mood disorders – from talk therapy and counseling to prescribed medication – Dr. Terpeluk suggests that the most important thing is to experience the underlying causes of the fear that you are about to get to the roots.

“Anxiety is better addressed by looking at what’s causing it in your life rather than figuring out what drugs can reduce it,” says Dr. Terpeluk.

It could help with cancer-related symptoms

CBD can help with nausea, vomiting, and weight loss from chemotherapy treatments. The FDA has approved three cannabis-related products to help relieve these symptoms and increase the appetite of AIDS sufferers. These drugs all contain a certain amount of THC or synthetic THC and are not just CBD alone.

However, some studies seem to suggest that CBD can help reduce the size of tumors and stop the spread of cancer cells in skin cancer, breast cancer, prostate cancer, and more. As with other areas of study, more human clinical trials are needed to understand the full effects of CBD on various cancers.

What are the side effects or risks of CBD?

When you buy CBD oil and other products online or from a local supplier, Dr. Terpeluk doesn’t really have a way of telling the purity of the CBD you’re using as it could get mixed up with other cannabinoids, like the dangerous Delta-8 or THC.

“It’s a little bit mysterious. It’s not as harmless as you think, ”says Dr. Terpeluk. “If you’re taking CBD oil because you buy it in the market, there is a very high chance you will get a positive THC drug test because it may actually contain THC.”

CBD can also affect a wide variety of medications, including pain relievers, antidepressants, antipsychotics, and more. It can also cause several side effects, which could include:

The best advice? Before considering CBD oil or any other CBD product, it is important to speak to your doctor to decide if it is safe for you and if it does not have harmful interactions with the medications you are currently taking.

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Innovations and Advancements in the $4.6 Billion CBD Market



The company invites investors, analysts and advisors to participate in its real-time interactive fireside chat

SOUTHEASTON, MA / ACCESSWIRE / January 19, 2022 / Pressure BioSciences, Inc. (OTCQB:PBIO) (“PBI” and the “Company”), a leader in the development and sale of innovative, diversified, pressure-based instruments, consumables and services for the global food and beverage industry, Biotherapeutic and personal wellness industries today announced the Company’s participation in the January 20 webinar, “Innovations and Advances in the CBD Market,” sponsored by the FORCE Family Office. This real-time, interactive “fireside chat” features three companies that have released or are about to release important, innovative products and services and/or advancements in the CBD space.

DATE: Thursday, January 20, 2022 (noon ET)
REGISTER: Click here to register for the FORCE webinar


  • Druck BioSciences, Inc. (OTCQB: PBIO) plans to release its revolutionary Ultra Shear Technology™ (UST™) platform for the production of water-soluble, long-term stable, highly bioavailable nanoemulsions from oil and water (e.g. CBD oil and water) in mid-2022. Mr. Richard T. Schumacher, Founder and CEO, will be present as a panelist.

  • ProVerde Laboratories (Private) is a highly respected analytical testing laboratory that brings quality and integrity to the cannabis space. dr Christopher Hudalla, Founder and CSO, was recently named one of the Top 10 Influencers in Cannabis Science. dr Hudalla will be a panelist.

  • The Alkaline Water Company (NASDAQ:WTER) is a fast-growing company that recently launched an innovative CBD-infused bottled water to bring functional benefits to consumers. Mr. Richard “Ricky” Wright, Founder and CEO, will participate as a panelist.

  • FORCE Family Office is the largest network of family offices in the United States. CEO Steven Saltzstein will be the moderator of the webinar.

The story goes on

Selected recent key announcements – PBIO

  • PBIO produces CBD oil nanoemulsions with 18 months of rock-solid stability

  • Plans announced for UST demo and toll manufacturing facilities on US West and East Coasts

  • Second US patent granted for revolutionary UST platform

  • UST successfully converts neem oil into a novel, highly effective nanoemulsion for use in agrochemicals

  • UST successfully nanoemulsified astaxanthin – one of the most powerful antioxidants in the world

  • PBIO receives three international patents for its innovative UST platform

  • PBIO and Ohio State University announce the formation of a food industry consortium to advance the commercialization of the company’s UST technology platform

  • PBIO targets the efficacy of therapeutics with improved drug delivery and dose security through UST processing

About FORCE Family Office

FORCE is the largest network of family offices in the United States with a significant and growing international footprint. In 2020 alone, they hosted more than 160 events, a number they expect to surpass each year. Her team is dedicated to helping family offices efficiently and successfully connect with private and public companies for co-investments, research, education and philanthropy.

About Pressure BioSciences, Inc.

Pressure BioSciences, Inc. (OTCQB: PBIO) is a leader in the development and distribution of innovative, diversified, pressure-based solutions for the global life sciences and other industries. Our products are based on the unique properties of both constant (ie static) and changing (ie Pressure Cycle Technology or PCT) hydrostatic pressure. PCT is a patented technology platform that uses alternating cycles of hydrostatic pressure between ambient pressure and ultra-high pressure to safely and reproducibly control biomolecular interactions (e.g. cell lysis, extraction of biomolecules). Our primary focus is the development of PCT-based products for biomarker and target discovery, drug design and development, characterization and quality control of biotherapeutics, soil and plant biology, forensics and anti-bioterror applications. In addition, major new market opportunities have arisen using our pressure-based technologies in the following areas: (1) Using our recently acquired, patented technology from BaroFold, Inc. (the “BaroFold” Technology) to enable entry biopharma contract services sector and (2) the use of our recently patented, scalable, high-efficiency, pressure-based Ultra Shear Technology (“UST”) platform to (i) form stable nanoemulsions from otherwise immiscible liquids (e.g., oils and water) and to ( ii) to produce higher quality, homogenised, longer shelf life or room temperature stable, low acid liquid foods that cannot be effectively preserved with existing non-thermal technologies.

Forward-Looking Statements

This press release contains forward-looking statements. These statements relate to future events or our future financial performance and involve known and unknown risks, uncertainties and other factors that may cause actual results, levels of activity, performance or achievements of our or our industry to differ materially from future results or levels activities, performance or achievements expressed, implied or inferred by these forward-looking statements. In some cases, you can identify forward-looking statements by using words such as “may”, “will”, “should”, “could”, “would”, “expects”, “plans”, “intends”, “anticipates”, “believes”, estimates”, “anticipates”, “forecast”, “potential” or “continue” or the negative of such terms and other similar terminology. These statements are only predictions based on our current expectations and projections about future events. You should not place undue reliance on these statements. When evaluating these statements, you should pay particular attention to various factors. Actual events or results may differ materially. These and other factors could cause our actual results to differ materially from any forward-looking statements. These risks, uncertainties and other factors include, but are not limited to, the risks and uncertainties discussed under the heading “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2020 and other reports filed from the company from time to t I am with the SEC. The Company assumes no obligation to update the information contained in this press release, except as required by law.

For more information about PBI and this press release, please click on the following website link:

Please visit us on Facebook, LinkedIn and Twitter.

Press contacts:

Richard T. Schumacher, President and CEO (508) 230-1828 (T)
Jeffrey N. Peterson, Chairman of the Board (650) 812-8121 (T)

SOURCE: Pressure BioSciences Inc.

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Martha Stewart CBD Launches its First-Ever Category Expansion with New Line of CBD Wellness Topicals



New Super Strength CBD Cream, Sleep Science CBD Cream and Daily De-Stress CBD Cream complete Martha’s wellness portfolio

SMITHS FALLS, ON and NEW YORK, January 19, 2022 /PRNewswire/ — Martha Stewart CBD today introduced Martha Stewart CBD Wellness Topicals, marking the brand’s first-ever category expansion in its growing CBD portfolio. Martha Stewart CBD offers consumers an easy way to meet their needs throughout the day with convenient and proven CBD products – including gummies, oils, softgels and the new CBD wellness themes. Martha Stewart CBD Wellness Topicals offer simple solutions that are easy to use and love and are part of Martha’s wellness portfolio.

Martha Stewart with the new line of Martha Stewart CBD Wellness Topicals (CNW Group/Canopy Growth Corporation)

The topical line of products is designed to improve daily well-being in specific ways. It consists of the Super Strength CBD Cream for muscle recovery, the Sleep Science CBD Cream for better sleep and the Daily De-Stress CBD Cream for stress management. Each product is formulated with market-leading concentrations of CBD, powerful co-actives, and proven aroma technology specifically formulated for each need, all carefully balanced for optimal results.

“I believe that living the good life can be simplified by focusing on practical and effective solutions, which is why I developed this series of CBD wellness topics with the Canopy Growth team,” says Martha Stewart. “I’m excited to improve the daily lives of our customers through proven formulations that make wellness accessible and convenient, with offerings that address muscle discomfort, sleep deprivation and stress.”

The potent formulas were developed by Martha in partnership with Marquee Brands and Canopy Growth Corporation, a global leader in diversified cannabis and cannabinoid-based consumer products. Leveraging Canopy Growth’s unparalleled consumer insights and continued innovation in this space, the new line utilizes cutting-edge aroma technology that has been shown to activate key areas of the brain to induce mood state changes in the areas of relaxation, reduced anxiety, emotion and memory.

The story goes on

“Martha Stewart CBD offers consumers simple solutions to improve their everyday wellness, and we’re excited to expand into a new category with the launch of these CBD wellness themes,” said Dr. Anna Persaud, Vice President of Skincare & Topicals at Canopy Growth. “Tried and tested on consumers, these high-quality, potent topical solutions are scientifically formulated and rigorously tested to the pinnacle of industry standards, and the new line represents the latest innovation in Martha Stewart’s growing portfolio of accessible CBD offerings.”

Martha Stewart CBD Wellness Topicals are formulated with US-sourced broad spectrum CBD, with the line boasting market-leading CBD concentrations with the lowest price per mg of CBD compared to competitors. At launch, each SKU will be available in 20ml, 50ml and 150ml sizes.

Martha Stewart CBD Wellness Themes

  • Super strength CBD muscle recovery cream with powerful co-actives including Magnesium and Ginger

  • Sleep Science CBD cream for better sleep, with essential oils with aroma technology, including lavender and vetiver

  • Daily De-Stress CBD stress relief cream with aroma technology essential oils including Neroli and Ho Wood

For more information on these new offerings, visit where the full lineup is available, or follow @marthastewartcbd on Instagram. Martha Stewart CBD is now available in an affiliate program. Register to participate using the link here:

About Canopy Growth Corporation
Canopy Growth (TSX:WEED,NASDAQ:CGC) is a leading global diversified cannabis and cannabinoid-based consumer goods company driven by a passion to improve lives, end prohibition and empower communities by unleashing the full potential of cannabis . Leveraging consumer insight and innovation, we offer product variations in premium dried flower, oils, softgels, infused beverages, edible and topical formats, and vaporizer devices from Canopy Growth and industry leader Storz & Bickel. Our global medical brand, Spectrum Therapeutics, markets a range of full-spectrum products using their color-coded classification system and is a market leader in both Canada and Germany. Through our award-winning Tweed and Tokyo Smoke banners, we reach our adult consumers and have built a loyal following by focusing on quality products and meaningful customer relationships. Canopy Growth has entered the health and wellness consumer space in key markets including Canada, The United Statesand Europe through BioSteel Sports Nutrition and This Works skin and sleep solutions; and has launched additional hemp-derived CBD products The United States through our CBD brands First & Free and Martha Stewart. Canopy Growth has an established partnership with Fortune 500 alcohol leader Constellation Brands. Visit for more information.

About marquee brands
Marquee Brands is a leading global brand owner and marketer. Owned by investor funds managed by Neuberger Berman, one of the world’s leading employee-owned investment managers, Marquee Brands targets high quality brands with strong consumer awareness and long-term growth potential. Marquee Brands strives to identify brands across consumer product segments with the aim of expanding their reach across retail channels, geographies and product categories while preserving brand heritage and enhancing the ultimate consumer experience. Through its global team of professionals and partners, Marquee Brands monitors trends and markets to grow and manage brands in partnership with retailers, licensees and manufacturers through dedicated, impactful strategic planning, marketing and e-commerce. In 2019, Marquee Brands acquired the Martha Stewart brand, which reaches approximately 100 million consumers each month across all media and merchandising platforms. Martha Stewart is the founder of Martha Stewart Living Omnimedia and America’s most trusted lifestyle expert and educator. Their branded products can be found in over 70 million homes and have a growing retail presence in thousands of locations.

Logo: Canopy Growth Corporation (CNW Group/Canopy Growth Corporation)



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SOURCE Canopy Growth Corporation

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Cannabis Capsules Are Ultra-Efficient, But Are They Right For You?



This story originally appeared on Emjay

The future is here. Cannabis comes in an ultra-efficient smokeless pill form that you can take orally. It seems unconventional, but when you really think about it, most things come in pill form.


It’s not uncommon to see psychoactive compounds, medications, and dietary supplements in capsule or tablet form. It would be a lot weirder if you had to smoke your vitamins or your allergy medicine.

Before you run out and grab some cannabis pods, there are a few things you should know. The experience varies widely and the effects may not be for everyone.

RELATED: Berner launches “Caps by Cookies,” capsules that mix mushrooms and THC

What is a cannabis capsule?

Cannabis capsules take the extract of a cannabis plant and mix it with a type of carrier oil in pre-measured doses. The packaging will usually list how much THC and how much CBD is in each capsule. You swallow your pre-measured dose of cannabis just like you would swallow any other capsule or tablet.

Cannabis capsules are not an adjunct to smoking or vaping cannabis. You are an alternative. If you don’t like smoking or can’t smoke, cannabis capsules allow you to enjoy the high of your favorite strains without involving your lungs.

Hemp or CBD capsules are completely different

Labeling is crucial, and vague terms can sometimes be misleading. Hemp is cannabis and CBD is a cannabinoid. Hemp extract capsules, or CBD capsules, are also technically cannabis capsules. The main difference between the two is that hemp capsules will not get you high. Hemp contains less than 0.3% THC, which is insufficient to induce any noticeable psychoactive effects.

That doesn’t mean hemp extract or CBD are baseless. They’re a great way to naturally induce relaxation and create feelings of emotional well-being without altering your mind. If you want some of the benefits of weed but need to keep your mind sober, CBD capsules are great. This is a complementary way to enjoy cannabis. You can take CBD with weed without getting high.

RELATED: How to Choose the Right CBD Softgel Dosage

How do cannabis capsules work?

You swallow your cannabis capsule and it reaches your stomach. Your body begins to digest and filter the cannabinoids, including the THC. They are released slowly over time, producing a high that can last up to two hours to start and up to eight hours to finally finish.

Capsules can be very polarizing. This is going to sound like an absolute nightmare to some people. If you want to be able to control your high and have a good idea of ​​when it will end, capsules are definitely not for you.

If you have a high THC tolerance and use weed for its medicinal or wellness benefits, you’ll probably love the idea of ​​a capsule. Taking one low-dose capsule twice a day will give you benefits without making you feel too high to function. It’s the perfect means to an end.

How capsules compare to other forms

Cannabis capsules work very differently than other forms of cannabis. For some people, this is a selling point. Others might see it as a disadvantage. It all depends on how you want to enjoy your weed.

vaporize cannabis

Vaping cannabis is one of the most convenient ways to use cannabis. It’s not messy. There is no smoke, no ash and no lighter. You don’t have to grind, pack or roll anything. You don’t have to remove the resin from a pipe or bong. It’s also extremely concentrated. You can take a strong hit from a vape and quickly end your smoking session when you have a novel to write or a song to play. You will feel the effects almost immediately.

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