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Woman Slain in Horrific 1994 California Cold Case Was an Oneida N

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The 1994 death victim in Riverside, California was identified as an elderly woman originally from Oneida, according to authorities.

Patricia Cavallaro, born March 22, 1937 in the city of Oneida, was recently identified after police used DNA evidence to create the positive ID. For the past 27 years, the woman has been identified simply as a white elderly woman who was found murdered and partially buried in the desert in the Palms area of ​​Riverside County, California.

Last year, the Riverside County DA regional Cold Case Homicide Team had a DNA sample prepared for forensic genealogy, according to a notice from the Riverside County Sheriff. “This sample was obtained through the services of a private laboratory, Texas-based Othram Inc. Using genetic matches, the Cold Case team was able to find a potential match. A biological child was found and a DNA sample was presented to the state. “Missing and Unidentified Persons System.”

In mid-December, the California Department of Justice released a report with the unequivocal conclusion that the late woman was indeed Cavallaro, who was reported missing by her husband in 2001 and not seen by her son for more than 30 years, according to the New York Post. The authorities informed the Post that neither the husband nor her son are suspected. Police told the Post that the cause of death was still pending, but her decomposed body was found “partially buried in the sand and wrapped in white plastic wrapped with brown string and partially exposed to the elements,” the report said the body was found buried undiscovered in the shallow grave for about 1 to 3 months.

Patricia Cavallaro Police Sketch. (Riverside County DA Regional Murder Case Team)

Cavallaro left Oneida and moved to Bellflower, California after their marriage in 1956. According to the Post, she lived there with her husband and two children until she disappeared in 1994.

According to media reports, authorities used a private DNA service company called GEDmatch.com to track Cavallaro’s family tree to help locate family members. Cavallaro’s husband died in 2017.

It is not known whether Cavallaro still has relatives in the Oneida area today.

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Women’s Health

Dubai’s Arab Health to examine why women had fewer babies during Covid-19 pandemic

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Obstetrics and gynecology experts will meet at the Arab Health Summit in Dubai this month to discuss why women have decided not to have babies because of the pandemic.

The Arab Health Obstetrics and Gynecology Conference will discuss trends in women’s health, including the impact of Covid-19 on reproduction and fertility.

dr Human Fatemi, medical group leader at ART Fertility Clinics in Abu Dhabi, said the pandemic has caused people to reconsider their plans to have children.

As an infertility specialist, I would not worry about Covid-19 and pregnancy

dr Human Fatemi, Medical Group Leader of ART Fertility Clinics

“The pandemic has definitely shifted the desire to become parents and the desire to have a child,” he said.

“For some patients, especially women with reduced ovarian reserve and aging, the pandemic will significantly affect their ability to have children.

“As an infertility specialist, I would not be concerned about Covid-19 and pregnancy. The key message is to maintain hygiene, wear masks, ensure social distancing and be careful. If you have a reduced ovarian reserve and want to get pregnant, don’t delay.”

Several research results show a direct link between the pandemic and women’s desire to have children.

According to research by the United Nations Population Fund, public health crises and economic shocks have long been recognized as conditions that alter reproductive behavior.

Data from the US, Europe and East Asia show sharp falls in births as of October 2020 compared to the same months last year, suggesting that Covid-19 has caused short-term fertility declines in many countries.

Research from the Australian Institute of Family Studies shows that one in five Australian women changed their baby plans because of the pandemic, and one in seven women said it likely affected when they would have children, with most study cohorts ( 92 percent) decided to delay pregnancy.

This was supported by a study in the journal Proceedings of the National Academy of Science, which reported the link between the pandemic and births in 22 high-income countries and found particularly sharp declines in southern Europe – Italy (-9.1 percent), Spain (-8.4 percent) and Portugal (-6.6 percent).

But doctors said the research doesn’t prove there’s a greater risk for pregnant women. You should follow precautions and deliver babies safely.

dr Kiran Mehndiratta, a specialist obstetrician and gynecologist at NMC Specialty Hospital Abu Dhabi, told The National in May 2020 – during the peak of the first wave – that pregnant women are not at increased risk compared to others.

However, she added, it is important to know that pregnant women’s immunity is reduced to ensure the baby is not rejected by the mother as half of its genes come from the father.

That means people with pregnancy complications like diabetes or high blood pressure, which are known risk factors for severe Covid-19, could also be at higher risk.

Most of the “very small number” of pregnant women who die at NMC Specialty Hospital, where Dr. Mehndiratta works who tested positive for Covid-19 were also asymptomatic.

“Only a few of them gradually developed a cough,” she said.

This supports theories that suggest pregnant women are no more vulnerable to the effects of Covid-19 than others.

The Obstetrics and Gynecology Conference is a regular feature of Arab Health, taking place from 24th to 27th January at the Dubai World Trade Centre.

The conference will host several key sessions on fertility, reproduction and Covid-19, including a session on ‘Covid-19 and the Fetus’, presented by Prof Asma Khalil, who specializes in Obstetrics and Maternal-Fetal Medicine at St George’s University Hospital specializes. London. A session on ‘Covid-19 and the impact on fertility’ will be given by Dr. Johnny T Awwad, Executive Chairman of Women’s Services and Head of Reproductive Medicine at Sidra Medicine & Research Centre, Qatar.

Updated January 19, 2022 2:27 p.m

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Women’s Health

Menopause brings an onslaught of changes to women’s bodies. Why don’t we talk about it?

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Menopause affects 50 million women in the United States, especially when they are at the peak of their careers and personal relationships. It is usually diagnosed 12 months after a woman’s last period.

Menopause begins around age 51, on average, and brings with it a serious drop in estrogen levels that affects the body from head to toe, says Dr. Somi Javaid, a board-certified gynecologist and founder of HerMD, a growing chain of health clinics in Cinncinati specializing in menopause and sexual health.

She explains that women experience hot flashes, trouble sleeping and memory, increased anxiety and depression, dry skin, weight gain, joint problems, decreased sex drive, vaginal dryness, problems with orgasm, and no menstrual cycles for 12 straight months. And in the months or years leading up to menopause — a period known as perimenopause — there’s still some bleeding, and estrogen levels still drop, but not as much.

People don’t talk much about menopause because it’s a generational thing, says Sally Mueller, a former Target executive and now co-founder and CEO of wellness company Womaness.

“I’m 57, my mother hasn’t talked about her menopause. And so the baby boomers and even Gen Xers really grew up being uncomfortable talking about it because their moms didn’t talk about it. And I see it really, really changing with millennials. Millennials are breaking every taboo and starting to open the conversation, so thank goodness.”

Despite the physical symptoms, women at this stage feel confident, have wisdom to share, and feel empowered and creative, Mueller points out.

hormone replacement therapy

According to Javaid, hormone replacement therapy (HRT) is safe for millions of women and can effectively address many of the symptoms mentioned above, as well as other hidden problems such as bone loss and an increased risk of cardiovascular disease.

Timing is important with HRT. “When hormones are prescribed within the first five years of menopause, they are actually cardioprotective. As for the increased risk of breast cancer, yes, if you have an estrogen receptor or progesterone receptor positive tumor, you can definitely accelerate growth. However, we still haven’t proven that HRT actually causes the cancer cells to start in the first place. But for patients who have a history or a strong family history, or who have genetic mutations such as BRCA, we do not recommend hormone replacement therapy for them.”

Does HRT help women become younger again? Javaid says that in her 20 years of clinical practice, women have said their skin changes, acne disappears, and joints hurt less.

“Yes, patients are seeing a return or resolution of some of their ailments. But I want to be clear: I’m not going to take a 51-year-old patient and make her 21 again. But they definitely feel better.”

There are now non-hormonal options, such as radiofrequency treatments and CO2 lasers, that are used for vaginal dryness, Javaid points out.

Start early – learn and adapt

It’s important to understand that menopause can lead to longer-term health effects, and many women aren’t informed until they’re already through menopause, Mueller says. “It would be a much easier transition if they were educating themselves even in their 30s and early 40s.”

Javaid says she begins educating her patients in her 30s. “I always tell my patients: nobody knows your body better than you do. If your provider is not listening to you, you need another provider. … I truly encourage women to live their best life, to understand what’s going on with them, and to seek the care that fits both their choices and their lifestyle. I think the sooner they find out about this, the better they will do with their healthcare.”

Javaid says women need to eat differently, too, and she’s a big proponent of intermittent fasting to lower insulin levels, which helps with weight gain during menopause.

Also, turn to weight loads to counter osteoporosis and do pelvic floor strength training to maintain sexual function and stay continent, she adds. “We don’t want to pee on ourselves when we’re exercising, coughing, or laughing with friends.”

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Do advanced therapies have a place in women’s health?

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Lehr participated in a biotech showcase session titled “Women’s Health: Progress and Innovation Continue to Generate Investor Interest.” The panel included executives from Context Therapeutics, EndoCyclic Therapeutics, Gennev, iSono Health and Univfy.

What is women’s health?

Defining women’s health seems deceptively simple, but there are many definitions, according to Biotech Showcase panelists. For some companies and investors, it is defined by certain diseases, such as hormonal diseases or diseases that affect women differently than men. For others, the term is limited to just breast cancer.

An evolving term – femtech – has emerged to refer to technologies focused on women’s health. Panelists explained that the classification helped increase visibility and make investors (traditionally a male-dominated space) intrigued and motivated to explore and learn more about the category. Ultimately, the committee called for more female investors.

Recently, femtech-focused companies and products have emerged. But according to Lehr, the innovations of this group are only incremental improvements. What the industry needs are logarithmic changes that catalyze a massive step forward toward healing.

One such innovation that has the potential to create that logarithmic jump is immunotherapy, Lehr said. Investors are already interested in this space, and getting investors to invest in female cancer immunotherapy could be transformative.

Advanced therapies for women’s cancer

Lehr explained that Context Therapeutics is a mission-driven company dedicated to women’s oncology. The company strives to develop products that improve the quality of life for women living with cancer.

The Company’s lead candidate is Onapristone Extended Release (ONA-XR), a progesterone receptor antagonist that inhibits the progesterone receptor by binding to chromatin, which in turn downregulates cancer stem cell mobilization and blocks immune evasion. The progesterone receptor is a ligand-activated transcription factor that promotes progesterone-dependent cancers such as ovarian, uterine (endometrial) and breast cancer.

These cancers hijack progesterone to stimulate cancer cell proliferation, metastasis, regeneration and immune evasion. ONA-XR is currently being evaluated in four Phase II studies and the Company expects to report results from these studies in 2022.

Context is also developing Claudin 6 bispecific, an anti-CD3 x, anti-Claudin 6, antigen bispecific monoclonal antibody that redirects T cell-mediated lysis to malignant cells that express Claudin 6. Claudin 6 is a target for a tight junction protein and is particularly enriched in ovarian and endometrial tumors. The combination of precision medicine and immunotherapy aims to attack tumors directly without damaging normal tissue.

As excitement and innovation in the field continues to grow, Lehr and other Biotech Showcase panelists expressed optimism about near- and long-term progress in bringing advanced therapies and transformative technologies to the women’s health sector.

Do you have a unique perspective on your research related to women’s health or femtech? Contact the publisher today to learn more.

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